The Scientist 2018 04.pdf

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APRIL 2018 | WWW.THE-SCIENTIST.COM
NEURON
NETS
WRAPPED UP IN
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AND MORE
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APRIL 2018
Contents
THE SCIENTIST
THE-SCIENTIST.COM
VOLUME 32 NUMBER 4
COMPOSITE FROM © ISTOCK.COM/VICTOR_85; © 2018, LISA A. CLARK; NIAID/FLICKR
Features
ON THE COVER: ILLUSTRATION BY LISA CLARK
32
Make Me a Match
Multidrug combinations for cancer are
proving more effective than single drug
therapies, but identifying promising
pairings remains a challenge.
BY ANNA AZVOLINSKY
40
Inner Nets
Cellular wrappings called perineuronal
nets control brain plasticity and are woven
into memory and psychiatric disorders.
BY DANIELA CARULLI
46
Double-Edged Swords
Macrophages play numerous roles
within tumors, leaving cancer
researchers with a choice: eliminate
the cells or recruit them.
BY AMANDA B. KEENER
0 4 .2 01 8 | T H E S C IEN T IST
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