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a d e m e c u
m
V
LANDES
BIOSCIENCE
Aortic
Surgery
Jeffrey L. Ballard
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vademecum
Surgical Oncology
David N. Krag, M.D.
University of Vermont Medical School
Burlington, Vermont, U.S.A.
L A N D E S
B I O S C I E N C E
G EORGETOWN , T EXAS
U.S.A.
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VADEMECUM
Surgical Oncology
LANDES BIOSCIENCE
Georgetown, Texas U.S.A.
Copyright ©2000 Landes Bioscience
All rights reserved.
No part of this book may be reproduced or transmitted in any form or by any
means, electronic or mechanical, including photocopy, recording, or any
information storage and retrieval system, without permission in writing from the
publisher.
Printed in the U.S.A.
Please address all inquiries to the Publisher:
Landes Bioscience, 810 S. Church Street, Georgetown, Texas, U.S.A. 78626
Phone: 512/ 863 7762; FAX: 512/ 863 0081
ISBN: 1-57059-633-6
Library of Congress Cataloging-in-Publication Data
Surgical oncology / [edited by] David N. Krag.
p. ; cm. -- (Vademecum)
Includes bibliographical references and index.
ISBN 1-57059-633-6 (spiral)
1. Cancer--Surgery. I. Krag, David N. II. Series.
[DNLM: 1. Neoplasms--surgery. 2. Medical Oncology. QZ 268 S96105 2000]
RD651.S8832 2000
616.99 4059--dc21
00-057733
While the authors, editors, sponsor and publisher believe that drug selection and dosage and
the specifications and usage of equipment and devices, as set forth in this book, are in accord
with current recommendations and practice at the time of publication, they make no
warranty, expressed or implied, with respect to material described in this book. In view of the
ongoing research, equipment development, changes in governmental regulations and the
rapid accumulation of information relating to the biomedical sciences, the reader is urged to
carefully review and evaluate the information provided herein.
Dedication
This book is dedicated to Paul Gross, Ph.D. at the Unviersity of the Pacific.
It is a small gesture to recognize his influence as an outstanding educator
whose powerful messages have stood the test of time.
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Contents
1. Breast Cancer .................................................................... 1
Lorraine Tafra
Scope of the Problem: Incidence ................................................................. 1
Risk Factors ................................................................................................ 1
Prevention .................................................................................................. 3
Screening .................................................................................................... 3
Methods of Diagnosis ................................................................................. 4
Types of Breast Cancer ................................................................................ 5
Preoperative Evaluation ............................................................................... 6
Tr eatment Options ..................................................................................... 6
Tr eatment Outcomes ................................................................................ 12
Posttreatment Surveillance ........................................................................ 15
Special Considerations .............................................................................. 16
2. Melanoma ....................................................................... 18
Lee W. Thompson, Laurence H. Brinckerhoff, and Craig L. Slingluff, Jr.
Scope of the Problem ................................................................................ 18
Risk Factors for the Development of Melanoma ....................................... 18
Screening for Melanoma ........................................................................... 19
Methods of Diagnosis ............................................................................... 20
Preoperative Evaluation ............................................................................. 20
Staging ...................................................................................................... 22
Tr eatment ................................................................................................. 24
Distant Metastasis ..................................................................................... 25
Adjuvant Therapy ..................................................................................... 26
Experimental Therapy ............................................................................... 27
Posttreatment Surveillance ........................................................................ 27
Special Considerations .............................................................................. 28
3. Nonmelanoma Skin Cancers ........................................... 31
Paul L. Baron
Introduction ............................................................................................. 31
Scope of the Problem ................................................................................ 31
Risk Factors .............................................................................................. 31
Screening .................................................................................................. 33
Diagnosis .................................................................................................. 34
Preoperative Evaluation ............................................................................. 37
Staging ...................................................................................................... 37
Tr eatment ................................................................................................. 37
Posttreatment Surveillance ........................................................................ 39
Unusual Tumors ....................................................................................... 40
Special Considerations .............................................................................. 42
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